Medicina Internacia Revuo

Demonstration of a therapy-induced regression of a carcinoma - twodimensional, threedimensional and musically

2024-04-09T13:13:05+02:00

This article presents an art project inspired by the exciting successes of the latest cancer-therapies, which make complete and sustained remissions of carcinomas a realistic outcome. Based on the histopathological specimens multidimensional graphics and sculptures are created. These objects of art can even be trasformed in musical compositions: by these means a multisensual art project succeeds in celebrating the modern successes of cancer-therapy and making them an instantaneous aesthetic experience.

Znaczenie niedoboru i nadmiaru żelaza w organizmie człowieka w patogenezie wybranych chorób systemowych

2024-04-09T13:16:40+02:00

Iron is a microelement necessary for the functioning of most organisms. Maintaining proper iron homeostasis is extremely important because both its deficiency and excess are harmful to the body.

The aim of the study was to present the importance of the role of iron in the pathogenesis of diseases caused by its deficiency or excess.

According to estimates, about 30% of the global population has health problems due to iron deficiency, which is the main cause of anemia. Excess iron in the body, caused by a genetic disorder of its absorption and, more often, other reasons, stimulates oxidative stress with the formation of active hydroxyl radicals with subsequent damage to cells and organs, as well as cell death dependent on iron metabolism – ferroptosis. A number of diseases that involve overloading the body with this element may be related to ferroptosis, causing cancer, neurodegenerative diseases, ischemia-reperfusion damage, and damage to the kidneys and gastrointestinal tract, including the liver, pancreas or lungs.

The sensitization spectrum to fungal allergens with atopic dermatitis and psoriasis in patients

2024-04-09T13:28:56+02:00

Introduction: The fungal allergy in the progress of atopic dermatitis (AD) and psoriasis (PS) are of special interest and determines the relevance in the study. The aim of the study to conduct a comparative analysis of the sensitization spectrum to fungal allergens in patients with atopic dermatitis and psoriasis.

Materials and methods. The study involved patients with AD (Group I, n = 53) and PS (Group II, n=53) and aged group (15-60) years old. Sensitization to fungal allergens was determined by skin prick testing using standardized fungal allergens: Candida albicans, Alternaria alternata, Aspergillus fumigatus, Cladosporium herbarum, Penicillium notatum (ThermoFisher Scientific, Dubai). The concentration of allergen-specific IgE to a mixture of fungal allergens: Penicillium notatum, Cladosporium herbarum, Aspergillus fumigatus, Alternaria alternata (ThermoFisher Scientific, Dubai) were determined by indirect immunofluorescent analysis on a ELISA analyzer. The IgE level test of positive was considered in IgE level ≥ 0.35 kU/l.

Results: The highest frequency of sensitization to fungi of the genus Cladosporium herbarum, Aspergillus fumigatus and Alternaria alternata were established In the group of patients with PS. The frequency of sensitization to fungi was higher in the group of patients with PS than in the group of patients with AD. Sensitization to a mixture of fungus allergens, according to the concentration of allergen-specific IgE, it were observed in the group of patients through compared with the group of patients in PS was : 2.7% and AD was 7.5%. Therefore, fungal allergy may play an important role in the etiopathogenesis of AD and PS.

Recommendation: The study of the diagnosis and treatment of these pathologies, including a specific allergological examination of patients with AD and PS. To study of the genotyping of fungi causing human infection.

The Clinical Outcomes in Routine Evaluation Short Form B (CORE SFB): Norms for an Irish Institute of Technology Student Sample

2024-04-09T13:35:19+02:00

A study of student mental health was conducted in an Irish university level college prior to the Covid-19 pandemic. The study had two principal objectives. The first of these was to provide a baseline examination of student mental health. The second aim was to explore the utility of several self-report mental health measures that had not previously been examined in an Irish population. This paper examines student mental health using one of these measures, the Clinical Outcomes in Routine Evaluation Short Form B (CORE SFB). Results from the achieved sample of 763 students are explored. Females self-reported significantly higher levels of mental distress on two of the CORE SFB subscales (the Wellbeing and Problems subscales) as well as on the Mean Total Score (MTS). Males were significantly more likely to endorse an item exploring threatening behaviour towards others. Final year students were also significantly more likely to self-report higher levels of mental distress on the Wellbeing, Problems and Functioning subscales, as well as on the MTS. Internal and test-retest reliability indicated support for the CORE SFB. Examination of the CORE SFB alongside the Mental Health Index (MHI) and the Brief Symptom Inventory (BSI 18) indicated convergent validity for this measure. Preliminary empirical percentile scores for the CORE SFB subscales and the total score were developed.

Zombies and weapons: examining blog responses to the Centers for Disease Control & Prevention’s (CDC) ‘Preparedness 101: Zombie pandemic’ entertainment-education initiative

2024-04-09T18:21:51+02:00

In an innovative attempt to engage adolescents and young adults in emergency preparedness, the Centers for Disease Control & Prevention (CDC) introduced its Preparedness 101: Zombie Pandemic entertainment-education initiative in 2011. This development received widespread attention and such popularity that the CDC’s website crashed as a result of the number of users attempting to access it. However, despite this atypical publicity, concerns have been raised about using this approach. Although some of the concerns focus on the efficacy of the zombie scenario to promote emergency preparedness, others have raised the issue of this theme promoting an unhealthy focus on weapons. To date the majority of this research noting the link between using such a theme and supporting a weapons culture has examined primary school children. This research uses content and reflexive thematic analysis to explore this potential unanticipated side-effect among a public audience. Five years of data from the CDC online blog was examined. Results indicate that over 10% of blog posts mentioned weapons. A number of themes of concern were identified from the blog posts relating to firearms, weapons, and killing. Although the CDC’s innovation is to be commended for its popular appeal, the use of a zombie theme links to wider media narratives that foreground weapons. As such it is recommended that such a theme should not be used in future public health interventions.