Prostate cancer and high specific prostate antigen levels in patients: a cross-sectional study
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Keywords

prostate-specific antigen
carcinoma
prostate cancer

How to Cite

1.
Alsherees HA, Al-Muhannak FHN. Prostate cancer and high specific prostate antigen levels in patients: a cross-sectional study. mir [Internet]. 17Sep.2023 [cited 13Jun.2024];30(2):146-53. Available from: https://interrev.com/mir/index.php/mir/article/view/188

Abstract

 

Background: The effect of different races possess, ethnic differences, and geographical have their respective reference ranges of serum prostate-specific antigen (PSA). The distribution of serum PSA in men without prostate cancer.

Aims: We studied the importance of early detection of LUTS patients in whom prostate cancer was suspected in the transition area of prostate cancer through transurethral resections(TURP), in the case of negative transrectal ultrasound (TRUS) biopsy.

Methods: A total of 63 patients undergoing TURP were evaluated of the period from July 2019 to March 2020. TRUS biopsy patients before TURP (group with cancer) and not (without cancer) were compared to the prostate detection rates. All charts, including prostate-specified antigen (PSA), digital rectal exam (DRE) results, TURP (including volume of resection and a pathology report), TRUS and TRUS biopsy results, were evaluated retrospectively.  Ethnicity has not been recorded since Al-Najaf  is multi-ethnic. Description statistics, statistic tables, the arithmetic medium, standard error, default and two extremes used to analyze the results.

Results: PSA values in different age groups were non significant difference in cancer detection rate between with  and without biopsy groups, the PSA mean was 4.7±1.6 ng / ml and 3.4±0.8 ng / ml,  and also IPSS  was 10.8± 1.4 and 9.1 ± 2.65 and p>0.05and while APEL(%) maen was 5.65±2.5 ng / ml and 10.5±1.35 ng / ml that significant difference between with  and without biopsy groups and  p<0.05.,  The detection rate for prostate cancer and PSA (p<0.05) have been positively correlated.

Conclusion : The results of serum PSA must be standardized by country and ethnic group. Ultimately, the diagnosis of prostatic carcinoma in a particular region will increase accuracy

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