Med.Inter.Rev. 2014, 103, 82-88.

L-Tryptophan and its derivatives in edible mushrooms species

Bożena MUSZYŃSKA1, Paweł KOMENDACKI1, Katarzyna KAŁA1, Włodzimierz OPOKA2, Jacek ROJOWSKI2

1.Department of Pharmaceutical Botany, Jagiellonian University Collegium Medicum, Medyczna 9 street, Kraków 30– 688, Poland
2.Department of Inorganic and Analytical Chemistry, Jagiellonian University Collegium Medicum, Medyczna 9 , 30–688 Cracow, Poland

Mushrooms are able to accumulate both primary and secondary metabolites. Medicinal and antioxidant properties of mushrooms are an excellent combination of their nutrition value. Recent studies have demonstrated that edible mushroom species contain non–hallucinogenic indole compounds and their derivatives. The indole skeleton is the basis of the substances serving important functions in the human body, such as serotonin and melatonin. These compounds fulfill the role of neurotransmitters or their precursors, exhibit antioxidant, anticancer, anti–aging actions, regulate the diurnal cycle in humans and participate in blood coagulation. These compounds and their derivatives are also anti–inflammatory and analgesic therapeutics.

Keywords: edible mushrooms, indole compounds, L–tryptophan, antidepressant agent, antioxidant activity

Oryginal language: English

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